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A 37-year-old man presents to the PMHNP based on a referral from his primary care physician, who suspects rapid cycling bipolar I disorder. Which of the following should be ordered to rule out an underlying medical etiology?

A. Dexamethasone suppression test

The dexamethasone suppression test is used primarily to assess for hypercortisolism or Cushing's syndrome, which is less commonly linked to mood cycling.

B. Liver function test

Liver function tests are important for monitoring medication metabolism but are not typically used to identify the etiology of rapid cycling bipolar disorder.

C. CSF 5-HIAA level

CSF 5-HIAA levels can reflect serotonin metabolism but are not standard for evaluating rapid cycling bipolar disorder and are rarely used in clinical practice.

D. Thyroid function tests

Thyroid dysfunction, including hyperthyroidism or hypothyroidism, can present with mood disturbances and contribute to rapid cycling in bipolar disorder; therefore, thyroid function tests are critical to rule out an underlying medical cause.

This question is an excerpt from Nurse Dive's nursing test bank - Mental Health Northern Kentucky University Proctored Exam 6. Take the full exam now


Full Explanation

Choice A reason: The dexamethasone suppression test is used primarily to assess for hypercortisolism or Cushing's syndrome, which is less commonly linked to mood cycling.

Choice B reason: Liver function tests are important for monitoring medication metabolism but are not typically used to identify the etiology of rapid cycling bipolar disorder.

Choice C reason: CSF 5-HIAA levels can reflect serotonin metabolism but are not standard for evaluating rapid cycling bipolar disorder and are rarely used in clinical practice.

Choice D reason: Thyroid dysfunction, including hyperthyroidism or hypothyroidism, can present with mood disturbances and contribute to rapid cycling in bipolar disorder; therefore, thyroid function tests are critical to rule out an underlying medical cause.


Similar Questions

QUESTION

A 51-year-old woman is diagnosed with primary osteoarthritis (OA) of the knee. The NP will educate the woman that which of the following could have contributed to or might worsen her OA?

A. Diabetes mellitus, a congenital abnormality, obesity

Diabetes mellitus is a metabolic disorder and is not a primary contributor to OA; congenital abnormalities alone are less commonly a major factor.

B. Overuse of joints, obesity, diabetes mellitus

While overuse and obesity contribute to OA, diabetes mellitus is not considered a key causal factor.

C. Overuse of joints, obesity, aging

OA risk increases with mechanical stress on joints, cumulative overuse, obesity that increases joint load, and aging-related degeneration of cartilage, making this the most accurate combination of contributing factors.

D. Overuse of joints, obesity, a congenital abnormality

Congenital abnormalities can predispose to OA in some cases, but aging is a far more common contributing factor overall.

Full Explanation

Choice A reason: Diabetes mellitus is a metabolic disorder and is not a primary contributor to OA; congenital abnormalities alone are less commonly a major factor.

Choice B reason: While overuse and obesity contribute to OA, diabetes mellitus is not considered a key causal factor.

Choice C reason: OA risk increases with mechanical stress on joints, cumulative overuse, obesity that increases joint load, and aging-related degeneration of cartilage, making this the most accurate combination of contributing factors.

Choice D reason: Congenital abnormalities can predispose to OA in some cases, but aging is a far more common contributing factor overall.

QUESTION

The psychiatric-mental health nurse practitioner has just diagnosed a 23-year-old man with bipolar disorder. He has had one manic episode with suicidal ideation and no depressive episodes to date. Which of the following is the most appropriate at this time?

A. Divalproex (Depakote)

Divalproex is an effective mood stabilizer, especially for rapid cycling or mixed episodes, but lithium is generally first-line for classic mania with suicidal ideation.

B. Lamotrigine (Lamictal)

Lamotrigine is more effective for bipolar depression than mania and is not ideal for initial treatment of a first manic episode.

C. Carbamazepine (Tegretol)

Carbamazepine is an alternative mood stabilizer but has more drug interactions and is not the preferred first-line for initial mania.

D. Lithium (Eskalith)

Lithium is considered first-line treatment for acute mania in bipolar disorder and provides prophylactic benefits; it is particularly indicated for patients with suicidal ideation.

Full Explanation

Choice A reason: Divalproex is an effective mood stabilizer, especially for rapid cycling or mixed episodes, but lithium is generally first-line for classic mania with suicidal ideation.

Choice B reason: Lamotrigine is more effective for bipolar depression than mania and is not ideal for initial treatment of a first manic episode.

Choice C reason: Carbamazepine is an alternative mood stabilizer but has more drug interactions and is not the preferred first-line for initial mania.

Choice D reason: Lithium is considered first-line treatment for acute mania in bipolar disorder and provides prophylactic benefits; it is particularly indicated for patients with suicidal ideation.

QUESTION

Which of the following aspects of bipolar disorder predicts a favorable response to lithium treatment?

A. Rapid cycling

Rapid cycling is associated with a poorer response to lithium, often requiring alternative or adjunctive therapies.

B. Euthymic intervals

Clear euthymic intervals between episodes are associated with classic bipolar disorder, which predicts a favorable response to lithium treatment.

C. Psychotic symptoms

Psychotic symptoms do not reliably predict lithium response; these patients may require additional antipsychotic therapy.

D. Mixed episodes

Mixed episodes often respond less predictably to lithium alone and may need combination therapy.

Full Explanation

Choice A reason: Rapid cycling is associated with a poorer response to lithium, often requiring alternative or adjunctive therapies.

Choice B reason: Clear euthymic intervals between episodes are associated with classic bipolar disorder, which predicts a favorable response to lithium treatment.

Choice C reason: Psychotic symptoms do not reliably predict lithium response; these patients may require additional antipsychotic therapy.

Choice D reason: Mixed episodes often respond less predictably to lithium alone and may need combination therapy.