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A nurse is caring for a client who is receiving neostigmine. Which of the following manifestations should the nurse identify as an adverse reaction to the medication? (Select all that apply.)

A. Hypoactive bowel sounds

Hypoactive bowel sounds: Neostigmine can actually increase gastrointestinal motility and may cause increased bowel sounds or even diarrhea, not hypoactive bowel sounds. Therefore, hypoactive bowel sounds are not an adverse reaction to neostigmine.

B. Sweating

Sweating: Sweating is a cholinergic effect and can be an adverse reaction to neostigmine. Increased sweating is a common sign of cholinergic stimulation.

C. Respiratory distress

Respiratory distress: Respiratory distress can occur as an adverse reaction to neostigmine, particularly if the client has a history of asthma or other respiratory conditions. Neostigmine can cause bronchoconstriction and excessive secretions, leading to respiratory distress.

D. Urinary retention

Urinary retention: Neostigmine is actually used to treat urinary retention by increasing bladder contraction. Therefore, urinary retention is not an adverse reaction to neostigmine.

E. Bradycardia

Bradycardia: Bradycardia (slow heart rate) is a significant adverse reaction to neostigmine due to its cholinergic effects on the heart. Increased acetylcholine levels can lead to excessive stimulation of the vagus nerve, resulting in bradycardia.

This question is an excerpt from Nurse Dive's nursing test bank - RN VATI Pharmacology S 2019 Proctored Exam. Take the full exam now


Full Explanation

Neostigmine is a medication classified as an acetylcholinesterase inhibitor. It is commonly used to treat myasthenia gravis and to reverse the effects of non-depolarizing neuromuscular blocking agents used during surgery. Adverse reactions to neostigmine are related to its cholinergic effects, which result from increased acetylcholine levels in the body.

Let's go through the options:

A. Hypoactive bowel sounds: Neostigmine can actually increase gastrointestinal motility and may cause increased bowel sounds or even diarrhea, not hypoactive bowel sounds. Therefore, hypoactive bowel sounds are not an adverse reaction to neostigmine.

B. Sweating: Sweating is a cholinergic effect and can be an adverse reaction to neostigmine. Increased sweating is a common sign of cholinergic stimulation.

C. Respiratory distress: Respiratory distress can occur as an adverse reaction to neostigmine, particularly if the client has a history of asthma or other respiratory conditions. Neostigmine can cause bronchoconstriction and excessive secretions, leading to respiratory distress.

D. Urinary retention: Neostigmine is actually used to treat urinary retention by increasing bladder contraction. Therefore, urinary retention is not an adverse reaction to neostigmine.

E. Bradycardia: Bradycardia (slow heart rate) is a significant adverse reaction to neostigmine due to its cholinergic effects on the heart. Increased acetylcholine levels can lead to excessive stimulation of the vagus nerve, resulting in bradycardia.


Similar Questions

QUESTION

A nurse is preparing to administer morphine 8 mg IV intermittent bolus to a client. The amount available is morphine 10 mg/mL. How many mL should the nurse administer?
(Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Full Explanation

To calculate the amount of morphine to administer, we can use the following formula:

Amount of medication (mL) = Desired dose (mg) / Concentration (mg/mL)

In this case, the desired dose is 8 mg and the concentration is 10 mg/mL.

Amount of medication (mL) = 8 mg / 10 mg/mL

Amount of medication (mL) = 0.8 mL

Therefore, the nurse should administer 0.8 mL of morphine.

QUESTION

A nurse is preparing to administer ampicillin/sulbactam 15 g via intermittent IV bolus, Available is ampicillin-sulbactam 1.5 g in 0.9% sodium chloride 100 mL to infuse over 30 min. The nurse should set the IV infusion pump to deliver how many mL/h?
(Round the answer to the nearest whole number. Use a leading zero if it applies in not use a trailing zero)

Full Explanation

To determine the infusion rate in mL/h, we need to divide the total volume (100 mL) by the total time (30 minutes) and then convert the result to hours.

100 mL / 30 min = 3.33 mL/min

To convert minutes to hours, we multiply by 60:

3.33 mL/min * 60 min/h = 199.8 mL/h

Rounding to the nearest whole number, the nurse should set the IV infusion pump to deliver 200 mL/h.

QUESTION

A nurse is preparing to administer dopamine 5 mcg/kg/min by continuous IV infusion to a client who weighs 220 lb. Available is 400 mg of dopamine in 250 mL of 0.9% sodium chloride. The nurse should set the IV pump to deliver how many mi/hr? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)

Full Explanation

To calculate the rate at which the IV pump should deliver dopamine, we can follow these steps:

Step 1: Convert the weight of the client from pounds to kilograms.

220 lb ÷ 2.2 = 100 kg (rounded to the nearest whole number)

Step 2: Calculate the total dose of dopamine per minute.

5 mcg/kg/min × 100 kg = 500 mcg/min

Step 3: Convert the dose from micrograms (mcg) to milligrams (mg).

500 mcg/min ÷ 1000 = 0.5 mg/min

Step 4: Determine the infusion rate in milliliters per hour (mL/hr).

The total volume of the solution is 250 mL.

The total dose of dopamine is 400 mg.

So, the infusion rate is (0.5 mg/min ÷ 400 mg) × 250 mL = 0.3125 mL/min.

Step 5: Convert the infusion rate from mL/min to mL/hr.

0.3125 mL/min × 60 min/hr = 18.75 mL/hr (rounded to the nearest tenth).

Therefore, the nurse should set the IV pump to deliver 18.8 mL/hr (rounded to the nearest tenth).