Nursing practice questions with comprehensive rationales
NurseDive Free Nursing Practice Question
A. giving the drug with food in order to delay absorption
Giving the drug with food may delay absorption but does not affect the extent of the first-pass effect.
B. administering the drug in small, frequent doses
Administering the drug in small, frequent doses may help maintain therapeutic levels but will not significantly alter the first-pass effect.
C. limiting the client's protein intake and encouraging fluids
Limiting protein intake could reduce drug binding to proteins, but this is not a standard approach for managing first-pass metabolism.
D. administering the drug intravenously rather than orally
Administering the drug intravenously bypasses the gastrointestinal tract and liver, avoiding the first-pass effect, thereby increasing the amount of free drug available to body cells.
This question is an excerpt from Nurse Dive's nursing test bank - Med Surg Exam Antelope Valley College Proctored Exam. Take the full exam now
Full Explanation
A. Giving the drug with food may delay absorption but does not affect the extent of the first-pass effect.
B. Administering the drug in small, frequent doses may help maintain therapeutic levels but will not significantly alter the first-pass effect.
C. Limiting protein intake could reduce drug binding to proteins, but this is not a standard approach for managing first-pass metabolism.
D. Administering the drug intravenously bypasses the gastrointestinal tract and liver, avoiding the first-pass effect, thereby increasing the amount of free drug available to body cells.
Similar Questions
A patient asks how metformin works to control blood sugar. What is the nurse's best response?
A. "Metformin stimulates the pancreas to produce more insulin."
Metformin does not stimulate the pancreas to produce more insulin; that action is characteristic of sulfonylureas.
B. "Metformin increases the absorption of glucose in the intestines."
Metformin does not increase the absorption of glucose in the intestines; rather, it works by reducing the amount of glucose released into the bloodstream.
C. "Metformin decreases glucose production in the liver and improves insulin sensitivity."
Metformin primarily decreases glucose production in the liver and improves insulin sensitivity in peripheral tissues, which helps lower blood sugar levels. This makes it effective for managing type 2 diabetes.
D. "Metformin decreases the breakdown of fat in the body."
While metformin can have effects on fat metabolism, its primary action is not to decrease fat breakdown but to manage blood glucose levels.
Full Explanation
A. Metformin does not stimulate the pancreas to produce more insulin; that action is characteristic of sulfonylureas.
B. Metformin does not increase the absorption of glucose in the intestines; rather, it works by reducing the amount of glucose released into the bloodstream.
C. Metformin primarily decreases glucose production in the liver and improves insulin sensitivity in peripheral tissues, which helps lower blood sugar levels. This makes it effective for managing type 2 diabetes.
D. While metformin can have effects on fat metabolism, its primary action is not to decrease fat breakdown but to manage blood glucose levels.
Interpret and spell the abbreviation: tid
Enter the word only.
Full Explanation
Correct answer is three times a day.
The nurse is caring for a client who experienced a severe headache. When the prescribed dose of analgesics did not cause relief, the client took double the dosage 1 hour later. The nurse should assess the client for what adverse effect?
A. An allergic reaction
An allergic reaction is a possible response to medication, but it is not directly related to doubling the dosage.
B. Anaphylactic reaction
Anaphylactic reaction is a severe and rapid allergic response; while possible, it is not the most likely consequence of an overdose in this context.
C. Poisoning
Poisoning is a likely concern when a client takes double the prescribed dosage of analgesics, especially if the medication has a narrow therapeutic index or is known to cause toxicity at high doses.
D. Sedative effects
Sedative effects could occur depending on the analgesic used, but poisoning is a more pressing concern following an overdose.
Full Explanation
A. An allergic reaction is a possible response to medication, but it is not directly related to doubling the dosage.
B. Anaphylactic reaction is a severe and rapid allergic response; while possible, it is not the most likely consequence of an overdose in this context.
C. Poisoning is a likely concern when a client takes double the prescribed dosage of analgesics, especially if the medication has a narrow therapeutic index or is known to cause toxicity at high doses.
D. Sedative effects could occur depending on the analgesic used, but poisoning is a more pressing concern following an overdose.