Nursing practice questions with comprehensive rationales
NurseDive Free Nursing Practice Question
Which effect of protein binding on drugs in the bloodstream is accurate?.
A. Inactivation of the drug.
Protein binding does not inactivate the drug. Instead, it can affect the drug’s distribution and bioavailability.
B. Increased risk of allergic reaction.
Protein binding does not directly increase the risk of an allergic reaction. Allergic reactions are typically immune responses to a drug, not a result of protein binding.
C. Precipitation of an idiosyncratic reaction.
An idiosyncratic reaction is an unusual or unexpected reaction to a drug, which is not related to protein binding.
D. Accumulation of the drug.
Protein binding can lead to the accumulation of the drug. Drugs often cannot cross membranes mainly due to the high molecular mass of the drug-protein complex, resulting in the accumulation of the active compounds.
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Full Explanation
Choice A rationale:
Protein binding does not inactivate the drug. Instead, it can affect the drug’s distribution and bioavailability.
Choice B rationale:
Protein binding does not directly increase the risk of an allergic reaction. Allergic reactions are typically immune responses to a drug, not a result of protein binding.
Choice C rationale:
An idiosyncratic reaction is an unusual or unexpected reaction to a drug, which is not related to protein binding.
Choice D rationale:
Protein binding can lead to the accumulation of the drug. Drugs often cannot cross membranes mainly due to the high molecular mass of the drug-protein complex, resulting in the accumulation of the active compounds.
Similar Questions
Which phenomenon occurs in the body as a person ages?.
A. Protein needs post-acute accentuate.
Protein needs do not necessarily accentuate with age. In fact, they may decrease due to reduced physical activity and metabolic rate.
B. Total fat content decreases.
Total fat content does not decrease with age. It’s common for fat distribution to change and increase in certain areas.
C. Total body water increases.
Total body water does not increase with age. It usually decreases due to the loss of muscle mass and increase in fat content.
D. Lean body mass decreases.
Lean body mass decreases as a person ages. This is a common phenomenon due to changes in cells and tissues.
Full Explanation
Choice A rationale:
Protein needs do not necessarily accentuate with age. In fact, they may decrease due to reduced physical activity and metabolic rate.
Choice B rationale:
Total fat content does not decrease with age. It’s common for fat distribution to change and increase in certain areas.
Choice C rationale:
Total body water does not increase with age. It usually decreases due to the loss of muscle mass and increase in fat content.
Choice D rationale:
Lean body mass decreases as a person ages. This is a common phenomenon due to changes in cells and tissues.
Which symptom is the most common with a hypersensitivity reaction to a medication?.
A. Urticaria.
Urticaria, also known as hives, is a common symptom of a hypersensitivity reaction to a medication.
B. Vomiting.
Vomiting can occur but it is not the most common symptom.
C. Wheezing.
Wheezing can be a symptom of a severe allergic reaction, but it is not the most common.
D. Anaphylaxis.
Anaphylaxis is a severe, life-threatening allergic reaction, but it is not the most common symptom.
Full Explanation
Choice A rationale:
Urticaria, also known as hives, is a common symptom of a hypersensitivity reaction to a medication.
Choice B rationale:
Vomiting can occur but it is not the most common symptom.
Choice C rationale:
Wheezing can be a symptom of a severe allergic reaction, but it is not the most common.
Choice D rationale:
Anaphylaxis is a severe, life-threatening allergic reaction, but it is not the most common symptom.
Which aspect of pharmacokinetics should the nurse be most concerned with when caring for a patient with abnormal functioning of hepatic enzymes?.
A. Absorption.
Absorption is not primarily affected by the functioning of hepatic enzymes.
B. Distribution.
Distribution is not the main concern when dealing with abnormal functioning of hepatic enzymes.
C. Excretion.
Excretion is mainly a function of the kidneys, not the liver.
D. Metabolism.
Metabolism is the aspect of pharmacokinetics most affected by the functioning of hepatic enzymes. The liver plays a crucial role in the metabolism of drugs.
Full Explanation
Choice A rationale:
Absorption is not primarily affected by the functioning of hepatic enzymes.
Choice B rationale:
Distribution is not the main concern when dealing with abnormal functioning of hepatic enzymes.
Choice C rationale:
Excretion is mainly a function of the kidneys, not the liver.
Choice D rationale:
Metabolism is the aspect of pharmacokinetics most affected by the functioning of hepatic enzymes. The liver plays a crucial role in the metabolism of drugs.